Edward Kelley

Edward Kelley was an English occult researcher who traveled across Europe with his partner, John Dee, developing a method to transmute base metals into gold using alchemy. He also calmed to be able to commune with spirits and angels threw a mirror belonging to Sir Dee.

Nioh
Edward Kelley is the main antagonist of Nioh, having been created by John Dee to gather all of England's amrita in the war effort against Portugal. In the Tower of London,  Sir Dee tasks him with going to Japan to take the country's amrita and return it to England. When he is confronted by Wiliam, he captures his Guardian Spirit, Saoirse, and escapes to Japan.

William first finds Kelley in Kyushu masquerading as Muneshige. After the two fight, Kelley steals the amrita in the caverns and disappears. He later is shown to be in the service of Mitsunari, empowering the Western Army's soldiers with amrita. During the Battle of Sekigahara, Kelley reveals that he plans to resurrect Nobunaga Oda.

When William reaches a newly reconstructed Azuchi Castle, Kelley reveals the resurrected Nobunaga. After the Demon King decides to spare William and die again, Kelley is incensed to use is Uroboros and Saorise's energy to summon Yamata no Orochi. William slays it and kills Kelley. Before his death, the alchemist reveals that he was working for John Dee, the Queen's adviser, and that he is one of many clones. William travels back to the England and confronts the man.